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Although Neptune and Uranus are incredibly cold, there are even colder places in the universe. The record holder for coldest is the Boomerang gas-dust cloud, a protoplanetary nebula 5,000 light-years away. The temperature there reaches minus 272 °C.
Nothing in the Universe can be colder than minus 273 °C. This temperature is considered absolute zero because at it, the tiny particles and atoms that make up everything stop moving, preventing further cooling. This means that we are unlikely to ever find a colder region in the Universe than the Boomerang Nebula.
